银屑病与动脉粥样硬化免疫学发病机制的联系

The Correlations Between Psoriasis and Atherosclerosis in Immunologic Pathogenesis

摘要:

银屑病和动脉粥样硬化均属慢性炎症性疾病,在形态学上均表现为“斑块”,但受累的靶器官不同。临床流行病学研究提示银屑病与动脉粥样硬化存在相关性。现从两者的免疫学机制和炎症通路切入,对两者免疫学发病机制的联系做一文献综述。

Abstract:

Psoriasis and atherosclerosis are both chronic inflammatory diseases, and share the common basic lesion of “plaque”, which affect different target organs. Clinical epidemiological studies suggest the correlations between psoriasis and atherosclerosis, and those in immunologic pathogenesis are reviewed in this essay from the perspective of immunological mechanisms and inflammatory pathways.