特定微生物感染与动脉粥样硬化相关性的研究进展

Research progress on the relationship between specific microbial infection and atherosclerosis

摘要:

动脉粥样硬化(As)是全球人群主要死亡原因之一,主要病因为高脂血症、高血压和肥胖等。然而,在规避了传统风险后,As仍有进展的可能。微生物感染因素近年来在As中的作用日益受到重视,该文综述了感染与As之间的相关性,并着重介绍了幽门螺杆菌、肺炎衣原体和人类免疫缺陷病毒(HIV)和巨细胞病毒等微生物感染促进As发展机制方面的研究进展,旨在进一步阐明微生物感染与As之间的相关性,为As的防治研究提供新思路。

Abstract:

Atherosclerosis (As) is one of the main causes of death in the global population. The main causes are hyperlipidemia, hypertension, obesity, etc. However, after avoiding traditional risks, As may still progress. In recent years, the role of microbial infection factors in As has been increasingly valued. This article reviews the correlation between infection and As, and focuses on introducing the research progress on the mechanisms by which microbial infections such as Helicobacter pylori, Chlamydia pneumoniae, human immunodeficiency virus (HIV), and cytomegalovirus promote the development of As, aiming to discover the correlation between microbial infections and As and provide new ideas for the prevention and treatment of As.