载脂蛋白A1结合蛋白对血管新生及心血管疾病的作用研究进展

Research progress on the role of apolipoprotein A1 binding protein in angiogenesis and cardiovascular diseases

摘要:

血管新生是动脉粥样硬化(As)斑块发展的关键环节,抑制血管新生有助于斑块稳定并降低相关心血管事件风险。载脂蛋白A1结合蛋白(A1BP)是一种重要的分泌蛋白,越来越多的研究表明,其在血管新生的调控中发挥重要作用。该文旨在阐述A1BP对血管新生及心血管疾病的作用机制,为心血管疾病的临床治疗提供新的思路。

Abstract:

Angiogenesis is a key link in the development of atherosclerotic plaques. Inhibiting angiogenesis contributes to plaque stabilization and reduces the risk of related cardiovascular events. Apolipoprotein A1 binding protein (A1BP), an important secretory protein, has been shown in a growing body of research to play a significant role in the regulation of angiogenesis. This article aims to elucidate the mechanisms of action of A1BP on angiogenesis and cardiovascular diseases, thereby providing new perspectives for the clinical treatment of cardiovascular diseases.